11 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... (SLE), Sjogren's ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... /systemic sclerosis ... #Lupus #Erythematosus ... #SLE #Summary # ... diagnosis #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
(CNS) involvement ... and treatment can ... Inflammatory causes ... • Sjögren syndrome ... • Systemic lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... SLE) Clinical ... #Lupus #Erythematosus ... #SLE #CNS #neurology ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... and CNS • Headache ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... (CNS) dysfunction ... lupus erythematosus ... [SLE], AOSD) • ... #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Syndrome Diagnosis ... #Syndrome #Rheumatology ... #Diagnosis #Management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
- Summary Clinical ... lupus erythematosus ... (SLE), polymyositis ... sclerosis. ... #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Diagnosis: Systemic ... lupus erythematosus ... SLE) • Urinalysis ... #diagnosis #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Antiamphiphysin antibodies ... #management #neurology ... #differential