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diagnosis antibodies antinuclear antineutrophil cryoglobulinemia cryoglobulins inflammatory neurology patterns prs pulmonary renal tafro thrombocytopenia types vasculitides
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... less common diseases ... • Systemic lupus ... polychondritis • Behcet disease ... spectrum disorder • ANCA-associated
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... lupus erythematosus ... ) • Systemic sclerosis ... • Sjögren syndrome ... #diseases
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• +ANA can be seen ... lupus erythematosus ... Syndrome (SS), ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... (ANA) - 95% - Initial ... block • Sjogren syndrome ... /systemic sclerosis ... #Lupus #Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... lupus erythematosus ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... • Autoimmune diseases ... 20% Sjögren's syndrome ... DDX: • ANCA (Antineutrophil ... lupus erythematosus
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... life-threatening diseases ... Inflammatory eye disease ... Pulmonary #Renal #Syndromes
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
multicentric Castleman disease ... lupus erythematosus ... s syndrome, ANCA-associated ... infection, rickettsial disease ... , Lyme disease,
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