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diagnosis rheumatology differential lupus sjogrens vasculitis arteritis behcet classification disease gca giantcell pathophysiology primary sarcoidosis temporal vasculitides
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... of hip (rare), Arthritis ... #systemic #erythematosus ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... like rheumatoid arthritis ... lupus erythematosus ... (SLE) Signs / ... Pathophysiology #Diagnosis #Signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... : Lungs: • Pleural ... syndrome Arthritis ... Induced Lupus: • Symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (Clinical Dx). ... : SLE, Reactive ... #diagnosis #management ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... signs/sx of inflammation ... vs infection vs malignancy ... GCA #Temporal #Signs ... #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... purpura: Strong sign ... ischemia • Skin: Erythematous ... exposure or Dx of malignancy
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... granulomas within the lungs ... renal failure Clinical ... Extrapulmonary: ankle arthritis ... #Signs #Symptoms
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... salivary ducts Clinical ... Malignancy Risk ... MALT Lymphoma • Lung
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