11 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
albumin gradient ... protein ≤ 2.5 g/dL: Cirrhosis ... , Massive liver ... #albumin #gradient ... #hepatology #differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... >1.1 g/dl): - Cirrhosis ... without cirrhosis ... #Differential # ... Diagnosis #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... Fitz-Hugh-Curtis syndrome ... Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... of portal HTN: ascites ... portal HTN: • Ascites ... INR, bilirubin, albumin
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... - Cirrhosis ... Causes #diagnosis #differential ... #hepatology #SAAG
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... #Differential #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... chemistry #diagnosis #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... vasculitis: 10%-16% Liver ... primary biliary cirrhosis ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... disease: cirrhosis ... Diagnosis (Clinical ... diuretic-resistant ascites ... - IV albumin
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
of orthodeoxia CLINICAL ... • Stigmata of cirrhosis ... : jaundice, ascites ... #cirrhosis #diagnosis ... #hepatology