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hematology liver treatment algorithm pathophysiology aflp causes hemophagocytic hlh lymphohistiocytosis obstetrics pregnancy rheumatology abnormal acromegaly activation arterial chemistry common comparison
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential # ... Diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... IgA, IgG, IgM (CVID ... gastric bypass), LFT ... #Workup #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... #Diagnosis #causes ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
infiltration) Differential ... Diagnosis: Viral ... Maternal Support - Critical ... #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Diagnosis Framework ... • Nephrotic Syndrome ... , Ischemic Liver ... #differential #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... hepatopulmonary #syndrome ... #diagnosis #management ... #treatment #hepatology
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