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diagnosis causes liver algorithm injury aflp lfts obstetrics pregnancy saag transaminitis acute albumin disease elevated fatty gradient hepatocellular hepatorenal hodgkins
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... cirrhosis or chronic hepatitis ... #Differential # ... Diagnosis #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... • Congenital: HELLP ... Trauma: Shock liver ... #Differential # ... Diagnosis #causes #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... • Infectious: Hepatitis ... biliary obstruction, HELLP ... #Injury #Differential ... Acute #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... • Infections: Hepatitis ... NAFLD, Autoimmune, HELLP ... #Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
, no necrosis HELLP ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... diagnosis #icp #HELLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Pregnancy - AFLP, HELLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Alcoholic hepatitis ... - Acute fatty liver ... Causes #diagnosis #differential ... #hepatology #SAAG
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... of portal HTN: ascites ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) - Differential ... - Alcoholic hepatitis ... - Massive liver ... Albumin #Gradient #Differential ... #Diagnosis #hepatology
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