8 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
albumin gradient ... syndrome, Massive liver ... #ascites #albumin ... #gradient #hepatology ... #differential #
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
made in the liver ... or not by the liver ... liverprof #Diagnosis #Hepatology ... #SAAG #Ascites ... Interpretation #Differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... Gradient (SAAG) ... - Differential ... - Alcoholic hepatitis ... Diagnosis #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Alcoholic hepatitis ... - Acute fatty liver ... Causes #diagnosis #differential ... #hepatology #SAAG
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... (SAAG>I.I), esophageal ... INR, bilirubin, albumin ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... , ↑Tbili/Dbili/AP ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Total Protein - Albumin ... concentration minus albumin ... gastric tumors • Hematology ... #ProteinGap #differential ... #diagnosis #hematology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
severe alcoholic hepatitis ... Diagnosis (Clinical ... diuretic-resistant ascites ... - IV albumin ... Hepatorenal #Syndrome #Hepatology