9 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... injury) • Ischemic ... Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential # ... Diagnosis #Management ... gastroenterology #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... those with CLD (± cirrhosis ... Injury (DILI) ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
hepatocellular pattern ... of liver injury ... though cholestatic pattern ... AIH #Diagnosis #Management ... #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
/or suspicious clinical ... evaluation of the pattern ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
disease management ... of UDCA for all patietns ... remain subject to clinical ... Cholangitis #diagnosis #management ... #summary #Hepatology