9 results
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #Differential # ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic #differential ... #Diagnosis #Management ... #gastroenterology ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... fold elevation, Bilirubin ... fold elevation, Bilirubin ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of hemolysis or liver ... as jaundice on clinical ... associated with bilirubin ... #hepatology #diagnosis ... #gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... function: INR, bilirubin ... #Hypertension #Differential ... Diagnosis #causes #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
infiltration) Differential ... Intrahepatic Cholestasis Management ... Maternal Support - Critical ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Syndrome #Diagnosis #Management
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
Carcinoma - AGA Clinical ... with Preserved Liver ... Systemic #Treatment #Management ... #Hepatology #Gastroenterology