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hematology management signs causes oncology algorithm infectiousdiseases syndromes treatment workup acidosis classification criticalcare deficiency disease erythematosus hemolysis hemolytic hodgkins infections
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... : Alcohol use, Liver ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #hematology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
Clinical manifestations ... of acute liver ... suppression, Anemia ... failure #Signs #Symptoms ... #Diagnosis
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Ischemia, Compartment Syndrome ... Clearance: Systemic liver ... in Short Bowel Syndrome
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... RBCs, muscle, liver ... associated with any symptoms
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... - Drugs (Beta lactam ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... #hematology #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The ... - Compartment syndrome ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential
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