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diagnosis hematology hemophagocytic hlh lymphohistiocytosis chronic common cvid differentiation hemeonc hypogammaglobulinemia immunodeficiency immunology leukemia lymphocytic sjogrens treatment variable workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... • Induce blast cell ... #management #hematology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... disease • Liver ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Low or absent NK cell ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... #Rheumatology # ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... Clinical Presentation ... - Elevated liver ... #Hematology #HemeOnc
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