23 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... transformation to acute ... Myelodysplastic #Syndrome ... #hematology #oncology
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... of acute liver ... lung injury, Acute ... #Signs #Symptoms ... #Diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... and hepatorenal syndrome ... • Cirrhosis/acute ... #causes #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... ) Differential Diagnosis ... Maternal Support - Critical ... #Pregnancy #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Rare: DAH, acute ... Differentiation #Syndrome ... #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... : HLH signs and ... presents as an acute ... #management #treatment
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... necrosis HELLP Syndrome ... and hemorrhage Acute ... Disease #Pregnancy #hepatology ... #differential #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... presence of metabolic syndrome ... Areas of diagnostic ... Abnormal #Algorithm #Hepatology ... #Differential #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... - ACS, AKI, acute ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology