14 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty ... Liver of Pregnancy ... (AFLP) Three syndromes ... Hemolysis, Elevated Liver ... #obstetrics #hematology
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... of acute liver ... abnormalities Liver ... Heart: High output ... #acute #liver #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Liver Failure ( ... ALF): • Liver ... • Gilbert's syndrome ... #differential #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... liver failure rapidly ... #Fatty #Liver # ... Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... Fatty Liver of ... features: Liver ... Disease #Pregnancy #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... liver failure; ... hepatocytes; in chronic liver ... has exhausted liver ... LiverFailure #Hepatic #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... the pattern of liver ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... • Cirrhosis/acute ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Diagnosis #causes #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... manifestation of ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology