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diagnosis management disease comparison cppd signs abnormal activation agglutinin anemia atlas beaus behcet calcium cll common cvid deposition differential diseases
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
life Causes and clinical ... Infections 2. ... Atopic diseases, Chronic ... spontaneous urticaria, Chronic ... Urticaria #diagnosis #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Laboratory Tests ... Differential #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Clinical Presentation ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... function tests ... Diagnosis #Management #Hematology ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... Recurrent and chronic ... signs #symptoms #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... disease • Liver ... syndrome, HIV) ... hypogammaglobulinemia #immunology #hematology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... joints (shoulders, wrists ... Chronic CPP Crystal ... • Metabolic syndrome ... Gout #Comparison #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... adults in the west ... Orange or Hep C Clinical ... weeks without infection ... workup #oncology #hematology
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
Chronic infections ... the Fingers Clinically ... Seen in liver disease ... illness, trauma, and cold ... seen in Reiter's syndrome
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
trauma (> 65 years old ... Chronic CPP Crystal ... Resembles RA • Chronic ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology
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