10 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... rare) Raynaud's phenomenon ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... gland) biopsy • Ocular ... salivary ducts Clinical ... #Syndrome #Rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Raynaud's phenomenon ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... Cryoglobulins: - Single ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... classification #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... white matter, spinal ... (Clinical Dx). ... signs #symptoms #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Autoimmune: thyroid, Sjogren ... Ocular- 50%: Ptosis ... myasthenia Diagnosis ... stimulation - Single ... Myasthenia #Gravis #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Arthralgias • Raynaud phenomenon ... pulmonary emboli, and ocular ... : • + Clinical ... Antiphospholipid syndrome ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... skeleton-sacroiliac joint and spine ... : • A clinical ... sites such as the collar ... #Rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... dermatomyositis, Sjogren ... Clinical Features ... #Rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
the most common clinical ... chondritis • Ocular ... Most common • Sjogren ... : • Clinical tests ... Polychondritis #rheumatology