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differential hematology causes management dermatology generalized hepatology infections liver physicalexam pruritus secondary systemic workup activation acute adrenalmass atlas beaus chronic
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... liver blood tests ... symptoms/signs ... #Liver #Enzymes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Myelodysplastic Syndromes ... Deficiency - Abnormal ... Tests • Liver
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Spiders - Enzyme ... Defects: Sickle cell anemia ... Laboratory Tests ... Blood Smear ↑ abnormal
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Algorithm - Systemic ... Function Tests/ ... Enzymes: • Cholestatic ... renal failure/uremia ... Myelodisplastic syndrome
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... Test for the respective ... thin smear • Signs ... node biopsy • Clinical ... UnknownOrigin #workup #diagnosis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... a cytoplasmic enzyme ... RBCs, muscle, liver ... red blood cell enzymes ... myocarditis, rheumatic fever
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Headache (45%) • Fever ... enzyme elevation ... enzymes ↑ • Mild ... anemia • Thrombocytopenia ... #HIV #diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... schistosomiasis • Pyemia ... Brucellosis Faget's Sign ... Brucellosis • Liver ... #Differential #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... extrahepatic source - Tests ... function may be abnormal ... Enzyme Elevation
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Algorithm Blood ... Function Tests/ ... Enzymes: • Cholestatic ... renal failure/uremia ... Myelodisplastic syndrome
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