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differential hematology algorithm causes eosinophilia generalized pruritus secondary behcet erythematosus immunology lupus lymphocytic management mds monoclonal myelodysplasia paraproteinemias pathergy primary
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> Invade Skin: ... lymphoma #Leukemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Asthma Tugs (vasculitis ... - Lymphomas ... - Systemic Mastocytosis ... - Chronic Eosinophilic ... #Causes #hematology
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
• Eosinophilic Leukemia ... GI, lung, skin), ... , T-cell leuk/lymphoma ... , B-cell lymphomas ... ), Systemic mastocytosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... • Leukemia ... syndrome Psychiatric ... #generalized #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... • Leukemia ... syndrome Psychiatric
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... Alpha & Mu) Skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... (malignancy), lymphoma ... - Allergic contact ... #diagnosis #dermatology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... Cell Leukemia ... #Syndromes #diagnosis ... #hematology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... tears, Ischemia, Leukemia ... , Lymphoma Ocular ... Recurrent and chronic ... signs #symptoms #rheumatology
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