19 results
hematology differential management leukemia causes chronic lupus purpura systemic workup acute agglutinin algorithm bruising classification cold common cvid dermatologic extravascular
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
SLL CLL Epidemiology ... Hepatomegaly • Skin ... , thrombocytopenia ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphoma (SLL) ... -> Invade Skin: ... Lymphoma (SLL) ... #Hematology #Oncology ... #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... ) (e.g. lupus, CLL ... , lymphoma, idiopathic ... #hematology #anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
or thrombocytopenia ... lymphoma (Richter ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... ) Blood (75%): Anemia ... #erythematosus ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #hematology #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... #workup #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... • Goodpasture syndrome ... • Angiocentric lymphoma ... #rash #diagnosis ... #rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
systemic lupus erythematosus ... Congenital heart disease ... infections - Vasculitis ... #Causes #peds #pediatrics ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... lymphoma • Evans ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
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