59 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
inhibitor) 2) Osmotic ... #pharmacology #nephrology ... #medications #sites
Chronic Diarrhea Differential Diagnosis
 • Inflammatory, Infectious: Recurrent C. diff, Giardiasis
 • Inflammatory, Non-infectious: IBD, Ischemia,
, Radiation • Osmotic ... Lactose intolerance, Medication ... Dysmotility: IBS, Medications
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
• Triamterene OSMOTIC ... #Diuretics #Medications ... summary #table #nephrology
Irritable Bowel Syndrome (IBS) Treatment Algorithm

IBS-Constipation:
 • Constipation: Osmotic laxatives
 • Abdominal pain: Antispasmodics

IBS-Diarrhea:
 • Diarrhea:
Syndrome (IBS) Treatment ... Constipation: Osmotic ... Syndrome #IBS #Treatment
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
canagliflozin 2) Osmotic ... Sites #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acetazolamide 2) Osmotic ... Pathophysiology #Nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
CAR-T therapy • Osmotic ... diagnosis #algorithm #nephrology ... #Medications
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Indications for ... Hyponatremia → Osmotic ... rate #management #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Diuretics • Osmotic ... Diagnosis #Causes #nephrology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Renal loss • Medication ... Hypomagnesemia • Osmotic