10 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... Sensory Changes - Differential ... • Myasthenia Gravis ... Lambert-Eaton Myasthenic Syndrome ... #Neurology #Differential
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... , Myasthenia Gravis ... Mitochondrial myopathy, Muscular ... #Causes #differential ... #diagnosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... #Differential # ... Diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Limb- proximal weakness ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... to ptosis and weakness ... Oculopharyngeal muscular ... #Differential # ... Diagnosis #ophthalmology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
non-localized EOM weakness ... such as cogan sign ... #PhysicalExam # ... clinical #video #ophthalmology ... #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
• Cauda Equina Syndrome ... foot and lateral calf ... claudication and weakness ... Myotomes #diagnosis #neurology ... sensory #motor #leg #physicalexam
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... • Symptoms and signs ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... and diplopia) • Vascular ... Behcet disease) Differential ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... pulse deficits vascular ... affects the skin, neurologic ... Myalgia and muscle weakness