10 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... to 1:1 F:M • Clinical ... Lupusreference #druginduced ... #lupus #sle #comparison
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... Farr assay) and lupus ... (60-70%) & drug-induced ... , neonatal lupus ... is clinically suspected
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... erythematosus (SLE ... disease (MCTD), Drug-induced ... Idiopathic Arthritis, Drug-Induced ... Biliary Cirrhosis, Drug-Induced
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Lupus Erythematosus ... SLE High risk ... Lupusreference #DrugInduced ... #SLE #Systemic ... #Lupus #Erythematosus
Drug-induced organizing pneumonia is commonly caused by Bleomycin and Cyclophosphamide and other drugs like Methotrexate, Amiodarone,
Drug-induced organizing ... Cyclophosphamide and other drugs ... #Clinical #Radiology ... #CTChest #DrugInduced ... OrganizingPneumonia #RadiologyAssistant
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... extremities Drug ... • Antihistone: Drug
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Fever is the main clinical ... SJIA], systemic lupus ... erythematosus [SLE ... ) • Sepsis • Drug-induced
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Epidemiology: -10% of all lupus ... to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... Lupusreference #DrugInduced
On the left a patient who is treated with cytotoxic drugs for a hematologic malignancy.
The radiographic
with cytotoxic drugs ... always consider drug-related ... #Clinical #Radiology ... #CTChest #DrugInduced ... DrugRelated #Fibrosis #RadiologyAssistant
It can be difficult to distinguish these three entities.
There are two diagnostic hints for further differentiation:
-
are difficult to see ... Post transplant - Drug ... penicillamine) #Clinical ... Attenuation #Comparison #RadiologyAssistant