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diagnosis differential hematology management neurology classification oncology workup arthritis chronic cll cord eosinophil eosinophilia hodgkins joint leukemia lymphocytic lymphoma lymphomas
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... skin and internal organs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... /SYMPTOMS: • CENTRAL ... impairment, Mood disorder ... Signs and symptoms ... /or cerebellar symptoms
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... indicated • For organ-specific ... signs or symptoms ... #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... Classic - Nodular Sclerosis ... pattern of spread, B symptoms ... Amy Chung, MD, MSc
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... and signs below ... : - Multiple sclerosis ... Sarcoidosis, Behcet disease ... differential #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... suggestive of multiple sclerosis ... : - Multiple sclerosis ... MCTD - Bechet disease
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Mechanical/degenerative disorders ... noninflammatory Signs ... constitutional symptoms ... Differential #Diagnosis #MSK ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... infiltrate any organ ... cells can indicate disease ... lymphoproliferative disorders
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... ingestion • B symptoms ... subtypes: - Nodular sclerosis ... check for other organ ... number of sites of disease
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... ethnicities Symptoms ... keratitis, uveitis, scleritis ... Kidneys • Other organs ... Polychondritis #rheumatology
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