20 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
by organ system ... The most common primary ... #Organs #Systems ... Diagnosis #Hematology #Signs ... #Symptoms
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... eosinophilia Primary ... and associated disorders ... Autoimmune thyroid disease ... Insufficiency #Signs
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin and internal organs ... skin thickening Signs ... and Symptoms: ... Hepatic: PBC (primary ... rheumatology #diagnosis #signs
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Infiltrative Disorders ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... Symptoms: Fatigue ... quadrant discomfort Signs ... of autoimmune disease
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... workup for specific symptoms ... indicated • For organ-specific ... signs or symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Electrolyte imbalances are common findings in many diseases. The kidney is a principally responsible organ for
findings in many diseases ... principally responsible organ ... broad range of signs ... presents with signs ... #electrolyte #algorithm
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... variability in disease ... normal mood - Primary ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... failure PBC Signs ... and Symptoms: ... but elevated as disease ... Lymphoma and solid organ