11 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - ACS, AKI, acute ... WBC >100k, + lab signs ... of end organ damage ... • Treatment:
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... ) • Acute: ... management #neurology #treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and damage of organs ... anterior/posterior MSK ... ), liver (pain/abnormal ... : ACUTE, fever, ... Diagnosis #Management #Signs
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... 500 mg QD until normal ... unless severe APLS, organ
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... presents as an acute ... with multiple organ
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
IDSA Algorithm for ... per minute) or abnormal ... oral antibiotic treatment ... or evidence of organ ... #SSTIs #Algorithm
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... ) - Internal organs ... Episcleritis Signs ... and Symptoms: ... Treatment: - Systemic
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
caucasian • Symptoms ... orbital pain, (Sub)acute ... Unilateral • Signs ... lesions (a), Brain: normal ... - Typical MS-like
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... infiltrate any organ ... microglobulin Treatment ... ’s lymphoma or acute
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Organ transplantation ... weeks incubation Acute ... Romana's sign ... /symptoms, positive ... Tests - check Acute