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diagnosis hematology oncology syndrome algorithm anemia aplastic apml behcet chronic classification cll differential differentiation disease disorders eosinophil eosinophilia hemophagocytic hlh
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... glucocorticoid treatment ... indicated • For organ-specific ... signs or symptoms ... Differential #diagnosis #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... megaloblastic anemia Treatment ... Anemia #diagnosis #management ... #treatment #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... When present, symptoms ... , signs, and complications ... PV #Diagnosis #Management ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... of end organ damage ... • Treatment: ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... with multiple organ ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... caucasian • Symptoms ... Unilateral • Signs ... - Typical MS-like ... #treatment #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... unless severe APLS, organ ... APML #diagnosis #management ... #hematology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
inflammation of multiple organs ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... infiltrate any organ ... microglobulin Treatment ... workup #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... check for other organ ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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