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diagnosis hematology management oncology differential algorithm acidosis activation acute agglutinin anesthesia anesthesiology aplastic apml brucellosis cancer carcinoma causes checklist chronic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Presentation: • Fever ... recurrent infections/fevers ... Treatment: ... #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... with leukopenia, anemia ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Diagnosing Brucellosis Epidemiological Exposures - Endemic Regions - Clinical Micro Lab Technicians - Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters - Unpasteurized
Constitutional: Fevers ... Weight loss - End Organ ... Genitourinary Diagnostic Tests ... CBC + Chemistry: Anemia ... Diagnosis #Criteria #Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... microglobulin Treatment ... Leukemia #diagnosis #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... agents given to organ ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Anemia (common) ... night sweats, fever ... Budd Chiari syndrome ... disease Imaging and Treatment ... test: abdominal
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... lab signs of end organ ... damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
emergency: permanent organ ... Treatment depends ... Actively maintained fever ... • Serotonin syndrome ... Diagnosis #Management #Workup
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Shock, Severe Anemia ... Ischemia, Compartment Syndrome ... Pain / Exercise, Fever ... Beta-Agonists, ↑ work ... Excerpted from original
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