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hematology management differential oncology classification eosinophilia fuo syndromes activation anemia anesthesia anesthesiology aplastic apml cancer causes checklist chronic cll dermatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... evaluation or workup ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Origin (FUO) - ... Further Workup ... Returning Traveler’ algorithm ... Test for the respective ... #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... Fever >38.5 2. ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Possible Algorithm for Workup of Fever of Unknown Origin (FUO) Tier 1 Workup: • CBC, comprehensive metabolic
Possible Algorithm ... for Workup of Fever ... • Additional tests ... #Origin #Workup ... #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
with response to treatment ... specific laboratory tests ... phase reactants, eosinophilia ... management #phenotypes #workup ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... Liver function tests ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... lab signs of end organ ... damage • Treatment ... #TLS #diagnosis ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
emergency: permanent organ ... Treatment depends ... Actively maintained fever ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
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