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diagnosis hematology management oncology activation algorithm apml cancer carcinoma chronic classification differentiation hemophagocytic hlh hodgkins leukemia lymphocytic lymphohistiocytosis lymphoma macrophage
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... infiltrate any organ ... microglobulin Treatment ... Leukemia #diagnosis #workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... formed or don’t work ... agents given to organ ... Workup: • Complete ... #diagnosis #hematology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... night sweats, fever ... Budd Chiari syndrome ... disease Imaging and Treatment ... express Laboratory tests
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... Subacute-Acute: • Common: fever ... Renal Failure Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... with multiple organ ... following: • Fever ... Low or absent NK cell ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Dyspnea • Fever ... Hodgkin Lymphoma Workup ... check for other organ ... Hodgkin Lymphoma Treatment
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... elevated risk of organ ... with repeated red cell
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... , MDS & Multiple ... Diagnosis: • Clinical tests ... affected tissue Treatment ... Polychondritis #rheumatology
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