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diagnosis management hematology oncology activetb differential latenttb tuberculosis algorithm apml bronchiectasis chagas chronic classification cll differentiation disease hemophagocytic hlh hodgkins
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • Fever • Weight ... Can involve any organ ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • Fever • Weight ... Can involve any organ ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... : Chronic infections ... , TB, Acute bacterial
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... SLE], AOSD) • Infection ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... with multiple organ ... following: • Fever ... #hematology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... • Mounier-Kuhn syndrome ... : TB, NTM, PNA ... dyskinesia • Young syndrome ... mycobacteria Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... weeks without infection ... microglobulin Treatment ... Leukemia #diagnosis #workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Differential Diagnosis: Infection ... Renal Failure Treatment
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
family Route of infections ... Organ transplantation ... mild (malaise, fever ... Confirmatory Tests ... and immunoblot (TESA
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... petechiae) • Frequent infections ... • Parvovirus infection ... agents given to organ ... Workup: • Complete
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