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hematology management tuberculosis activetb latenttb lymphoma syndrome acute apml chronic classification comparison differential differentiation emergencies hemeonc hiv hivaids leukemia ltbi
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
origin • Etiology ... e.g., HIV), EBV infection ... - Pel-Ebstein fever ... Etiology: - Infections ... NonHodgkins #comparison #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... weeks without infection ... microglobulin Treatment ... #workup #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Dyspnea • Fever ... Lymphoma Workup ... Lymphoma Treatment ... classification #hematology #oncology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • Fever • Weight ... Tuberculosis Diagnosis ... Tuberculin skin test ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • Fever • Weight ... Tuberculosis Diagnosis ... Tuberculin skin test ... #Diagnosis #Management ... #Treatment #ActiveTB
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
IDSA Recommendations ... and molecular diagnostic ... recommended for all ... #IDSA #Prevention ... #opportunistic
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Headache (45%) • Fever ... Presentations: • Opportunistic ... Labs: • CD4+ T-cell ... in which case opportunistic ... ) Treatment:
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Subacute-Acute: • Common: fever ... : Infection (sepsis ... management #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... work-up - If febrile ... days → add fungal work-up ... #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Parvovirus infection ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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