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differential management clinical cppd gout msk neurology signs algorithm als amyotrophic arthritis cardiology cardiomyopathy causes chondrocalcinosis comparison fungal gouty infections
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... distal to elbows/wrists ... and knees • Diffuse ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
Cardiomyopathy - Diagnosis ... ↑ "Right Sided-Symptoms ... Echocardiography, Cardiac MRI ... Cardiomyopathy, Systemic Sclerosis ... #differential #cardiology
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... tear (similar symptoms ... #Knee #patella ... #clinical #mri # ... #diagnosis #msk
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... circumscribed sclerotic ... diffuse chondral disease ... #clinical #Radiology ... #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Pathophysiology ... Presentation: - Disease ... course of the disease ... fasciculations Common Symptoms ... MRI: Brain, cervical
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... forefoot, ankles, knees ... Gout #Comparison #rheumatology ... #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... suggestive of multiple sclerosis ... : - Multiple sclerosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
(especially in knees ... affected — e.g., wrist ... #Signs #Symptoms ... #Pathophysiology ... #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... , particularly scleritis ... • Progressive symptoms ... oligoclonal bands • MRI ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... • Sclerosing mediastinitis ... extrapulmonary disease ... or meningitic disease ... Aspergillosis Pathophysiology
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