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diagnosis oncology rheumatology algorithm anemia cll differential disease hepatology leukemia lupus lymphocytic sle workup acquired activation agglutinin aih antinxp2 antinxp2dm
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
Rouleaux formation is common ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... Rebound effect from treatment ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... disorders • Shear ... vonWillebrand #Syndrome ... #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... immunophenotype Clinical ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... Lutzomyia verrucarum Clinical ... phase: Peripheral smear ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Orange or Hep C Clinical ... • Peripheral smear ... microglobulin Treatment ... workup #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... : • Nephrotic syndrome ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
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