18 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Management • ... vonWillebrand #Syndrome ... #treatment #hematology ... #differential
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... (l and II) Hepatic ... Algorithm #Causes #Hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... disease, Copper and ... Extravascular #Causes #differential ... #diagnosis #hematology
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
onto outstretched hand ... ), compartment syndrome ... I or Ill) • Ortho ... Forearm #Ulnar #Radiology ... Orthopedics #Proximal #MSK
Supracondylar Elbow Fracture
• Most common elbow fracture in children, peak age 5-7 
• When looking at
), compartment syndrome ... • ED Management ... Type l, DC with ortho ... Elbow #Humerus #Radiology ... #Orthopedics #MSK
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... • Rule out B12 and ... Algorithm #Causes #Hematology
Distal Radius Fracture 
Distal radius fracture is the most common orthopedic injury. Here's a quick summary.
•
carpal tunnel syndrome ... injury) • ED Management ... Sugar tong • Ortho ... Colles #Distal #Radiology ... #Orthopedics #MSK
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and ... hydroxyurea +/- TKIs and ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... - Intrauterine and ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology