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hematology causes anemia workup algorithm bruising oncology testing thrombocytopenia bleeding classification glomerular hemolysis nephrology nephrotic purpura rheumatology agglutinin aggregometry alopecia
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Differential Diagnosis ... Table Warm AIHA ... Cold Agglutinin Disease ... Differential #Diagnosis ... #Table #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... - Autoimmune (AIHA ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... with or without platelet ... Consider RBC membrane disorder ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #nonpalpable #dermatology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... Von Willebrand Disease ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Autoimmune: Warm AIHA ... #Differential # ... Diagnosis #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
without platelet ... MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Sequestration Disordered ... Platelet Function ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... lymphoproliferative disorder ... Diagnosis: • hemolytic ... younger pts) Differential ... #hematology #diagnosis
Nail diseases and disorders. - Spoon Nails (Koilonychia) - Pitting of Nails - Beau's Lines -
Nail diseases and ... Leukonychia (white spots ... ) #Diagnosis # ... #Differential # ... #Leukonychia #Table
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