6 results
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... be low, while ACTH ... Secondary AI = the pituitary ... Low ACTH leads to ... #endocrinology
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
diurnal, menstrual, and ... Prolactin #PRL #FeedbackLoop ... #endocrinology ... #pathophysiology ... #pituitary
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
- Pathogenesis and ... ACTH ... LH, FSH, TSH, ACTH ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
acromegaly, widening of hands ... GrowthHormone #GH #FeedbackLoop ... #endocrinology ... #pathophysiology ... #pituitary
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
- Check ACTH ... cortisol 30 min AND ... Step 3) Differentiate ... . problem with pituitary ... #Stimulation #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
macrognathia), ↑ hand ... malignancy Pathophysiology ... Differential Diagnosis ... TFT, LH, FSH & ACTH ... Diagnosis #Management #Endocrinology