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diagnosis hepatology algorithm alkaline alp management obstetrics phosphatase pregnancy abnormal acromegaly arterial biliary cholangitis cirrhosis comparison disease elevation embolism enzymes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... infiltration) Differential ... age • Monitor and ... Pregnancy #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Pruritis History and ... #Elevation #Differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
enzymes, and Low ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone: • Liver ... acromegaly, widening of hands ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
macrognathia), ↑ hand ... malignancy Pathophysiology ... GH stimulates liver ... Differential Diagnosis ... Diagnosis #Management #Endocrinology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... bone, placenta and ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... obstruction • ALP ... or higher • Liver ... bile ducts Differential
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
synthetic failure and ... in orange boxes and ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Drugs: - Oral and ... Syndrome, Ischemic Liver ... Venous #Arterial #pathophysiology ... #hematology #differential
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