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differential management causes guillain spinalcord syndromes algorithm cord hematology injury msk neuropathy spinal treatment acute aids anemia aplastic associated bee
NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
• Persistent bladder ... dysfunction, Severe bladder ... Recent diphtheritic infection ... #Syndrome #diagnosis ... #criteria #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... response preceding infection ... Clinical Features ... #Syndrome #diagnosis ... management #treatment #neurology
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Chemotherapy • Infectious ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... transplantation CLINICAL ... #Syndrome #diagnosis ... #management #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... level of injury, Bladder ... #diagnosis #pathophysiology ... symptoms #msk #orthopedics ... #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
disturbance • Bladder ... Differential Diagnosis ... cord infarct • HIV ... cord • Guillain-Barre ... #causes #neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
• Malignancy Infectious ... Tuberculosis • Epstein-Barr ... Hepatitis • HIV ... Pulmonary Disease Neurologic ... Chronic Fatigue Syndrome
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... and not direct infection ... #Tuberculosis #diagnosis ... differential #TB #neurology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
important, as early diagnosis ... pachymeningitis • HIV ... MRI lesions and clinical ... #neurology #noninflammatory ... #differential #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid
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