23 results
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Posterior hip ... wall • Anterior hip ... Signs/Symptoms ... pathophysiology #signs ... #symptoms #orthopedics
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... addisons #disease #endocrinology ... #diagnosis #signs
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... Hydroxylase #Deficiency #Signs ... #Symptoms #diagnosis ... #endocrinology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
65%, Can involve DIP ... • Scleroderma renal ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Diagnosis and Management ... fungal infection, HIV ... ketoconazole, etomidate) Symptoms ... Secondary #Diagnosis #Management ... #Endocrinology
What is a Boxer’s fracture?? Fracture of the 4th or 5th metacarpal neck
 - Common in
onto the hand Symptoms ... Management: - ... weeks Urgent orthopedics ... Overlying wounds or signs ... #Referral #Orthopedics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-OHD in the adrenal ... as "congenital adrenal ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Aseptic necrosis of hip ... Abdominal pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Inhibitors - Normal and Renal ... Incretins (GLP-I & GIP ... patients have renal ... #Pharmacology #Management ... Diabetes #DM2 #Endocrinology
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... patient has severe symptoms ... • Discuss with endocrinology ... — discuss with endocrinology ... #Hyponatremia #Management