20 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Utilizing Uric Acid ADH ... water retention 1) ... Serum Osmolarity ... 2) Urine Osmolarity
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... urea causes the hyponatremia ... True hyponatremia ... #hyponatremia #ADH
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 1) Is it hypotonic ... 2) Is ADH elevated ... Measure urine osmolality ... of symptomatic (seizures
Hyponatremia Diagnostic Algorithm
1) Check serum osmolality
2) Check urine osmolality
3) ADH Dependent - Check volume status, urine
Hyponatremia Diagnostic ... Algorithm 1) Check ... serum osmolality ... 2) Check urine osmolality ... 3) ADH Dependent
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... 1) Neurological ... Hypovolaemia → ADH ... SaltWasting #SIADH #Pathophysiology ... diagnosis #nephrology #hyponatremia
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
restriction: • Restrict 1 ... Saline: • If Urine osmolality ... antagonists: • Blocks ADH ... SIADH #Management #hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treatment Options 1. ... purposes, restrict to 1 ... NS • If Urine osmolality ... vaptans) • Blocks ADH ... SIADH #Management #hyponatremia
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management: 1. ... Manage ICP and Seizures ... agents = increase osmolarity ... Pressure #ICP #Pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Onset Alzheimer's (1% ... - Presenilin 1 ... dysfunction: myoclonic seizure ... AlzheimersDisease #Dementia #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
exertion/training - Seizures ... Dermatomyositis Clinical ... ALT Elevation 4:1 ... Aldolase ↑ • LDH ... Hyperuricemia • Hyponatremia