23 results
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
electrolyte abnormality caused ... among the possible causes ... asymptomatic to seizures ... in blood urea causes ... #hyponatremia #ADH
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... , ADH (appropriately ... 2) Is ADH elevated ... Measure urine osmolality ... of symptomatic (seizures
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Treat underlying cause ... : • Causes can ... Saline: • If Urine osmolality ... antagonists: • Blocks ADH ... SIADH #Management #hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... administered • This can cause ... NS • If Urine osmolality ... vaptans) • Blocks ADH ... SIADH #Management #hyponatremia
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
-> Withdrawal seizure ... Systemic effect -> Nausea ... vomiting, diarrhea, hyponatremia ... #SideEffects #Pathophysiology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
urea, uric acid, osmolarity ... If cause of AKI ... investigations depending on clinical ... fragmentocytes, LDH ... Diagnosis #nephrology #causes
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Manage ICP and Seizures ... = dilated BV = raises ... agents = increase osmolarity ... Pressure #ICP #Pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... dysfunction: myoclonic seizure ... AlzheimersDisease #Dementia #pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... severe clinical ... Rhabdomyolysis • Seizures ... Differential #Diagnosis #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... Etiology: • Pathophysiology ... the underlying cause ... with AEDs until cause