9 results
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... True hyponatremia ... #hyponatremia #ADH ... #Hypovolemia #EBV
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 2) Is ADH elevated ... Measure urine osmolality ... volume status (EABV ... of symptomatic (seizures
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Manage ICP and Seizures ... CO2 = dilated BV ... agents = increase osmolarity ... Pressure #ICP #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... >2400 Ul/ml, ↑ LDH ... treatment #summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Movement disorders, Seizure ... Disease, PRES Pathophysiology ... CNS #neurology #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... - HIV, CMV, EBV ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... /constipation, hyponatremia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
exertion/training - Seizures ... Dermatomyositis Clinical ... Aldolase ↑ • LDH ... Hyperuricemia • Hyponatremia
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Diagnosis: • Seizures ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... anemia (MAHA) Pathophysiology ... uncontrolled with ACEi, add ... Renal #Crisis #rheumatology