35 results
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... #Hyponatremia #Algorithm ... #Pathophysiology ... #Differential #Nephrology ... #UOsm #Osmolality
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Utilizing Uric Acid ADH ... retention 1) Serum Osmolarity ... 2) Urine Osmolarity ... Diagnosis #Algorithm #nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... urea causes the hyponatremia ... True hyponatremia ... #hyponatremia #ADH
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 2) Is ADH elevated ... Measure urine osmolality ... of symptomatic (seizures ... Treatment #management #nephrology
Hyponatremia Diagnostic Algorithm
1) Check serum osmolality
2) Check urine osmolality
3) ADH Dependent - Check volume status, urine
Hyponatremia Diagnostic ... 1) Check serum osmolality ... 2) Check urine osmolality ... 3) ADH Dependent ... #nephrology
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
Generalized Seizures ... Generalized seizures ... hyperglycemia, hyponatremia ... Classification #Diagnosis #Neurology ... #Signs #Symptoms
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Hypovolaemia → ADH ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology ... #hyponatremia #
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Saline: • If Urine osmolality ... antagonists: • Blocks ADH ... SIADH #Management #hyponatremia ... #nephrology #treatment
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
urea, uric acid, osmolarity ... investigations depending on clinical ... context and signs ... fragmentocytes, LDH ... Differential #Diagnosis #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
NS • If Urine osmolality ... vaptans) • Blocks ADH ... SIADH #Management #hyponatremia ... #nephrology #treatment