12 results
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
Osteosarcoma Most ... palpation) #Osteosarcoma
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
Chondroblastoma • Osteosarcoma ... sign • Parosteal Osteosarcoma
Diagram of different types of bone tumors that can occur around the knee on XRay -
Chondroblastoma • Osteosarcoma
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
most common • Osteosarcoma
Cyclophosphamide Pharmacology Summary

Mechanism of Action: Alkylating Agent
Indications: Solid tumors, Breast. bladder, endometrial. ovarian, testicular, osteosarcoma
Toxicities -
ovarian, testicular, osteosarcoma
Bone Tumor Location within the Skeleton

Epiphysis: 
Only a few lesions are located in the epiphysis, so
NOF, SBC, CMF, Osteosarcoma
Diagram of different types of bone tumors that can occur around the knee on XRay -
sign • Parosteal Osteosarcoma
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Cortical Bone • Osteosarcoma
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
and ↑ risk for osteosarcoma
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
cell tumor - Osteosarcoma