7 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
A1c Lowering Metformin ... DPP4 • Janumet (metformin ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... EricsMedicalLectures/ #Metformin ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Management of Polycystic Ovary Syndrome (PCOS)
Hyperandrogenism, Family Planning, Endometrial cancer prevention, Cardiovascular risk factor management
→ Weight
No FDA approved treatments ... Metformin 3. ... Letrozole (BMI >30 kg/m2 ... Syndrome #Management #endocrinology ... #gynecology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Line Treatment ... medication #Metformin ... Indications #Titration #Pharmacology ... #Diabetes #DM2
PCOS Treatment
1st line = weight loss
 • 5-10% weight loss can restore ovulatory cycles
 • Improvement
PCOS Treatment ... 14d q1-2 mo • Metformin ... waxing #PCOS #Treatment ... #management #endocrinology ... syndrome #obgyn #gynecology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
combo product with metformin ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
initiation of treatment ... FDA recommends, metformin ... ml/min per 1.73 m2 ... with metformin. ... evidence-based pharmacologic