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diagnosis amiodarone apml differentiation diuretics excretion hematology lung medications nephrology oncology pharmacology renal table toxicity toxicology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Altitude sickness • Diuretic ... irrigation • Management ... Torsemide) • Acute ... pulmonary edema ... • Lithium-induced
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
endothelial damage • Induce ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... Supportive Care: Diuresis ... APML #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
organizing pneumonia, ARDS ... toxicity (e.g., acute ... respiratory distress syndrome ... failure - Infectious ... #diagnosis #management
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