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hematology nephrology algorithm apml cancer capillary clarksons differentiation disease diuresis diuretics excretion fungal hypokalemia infections infectiousdiseases leak medications mycoses oncology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... with thiazide diuretic ... Rhabdomyolysis Treatment ... #Syndrome #diagnosis ... #nephrology #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... • Diagnosis of ... irrigation • Management ... Torsemide) • Acute pulmonary ... Tolvaptan) • Treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #management #hematology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... filling +++ (risk of pulmonary ... #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
host): • Chronic pulmonary ... symptoms • Rheumatologic ... Histoplasmosis Diagnosis ... MUCORMYCOSIS • Risk: Diabetes ... #Management #Infections
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... median age at diagnosis ... cardiovascular or pulmonary ... approved by the Food
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