42 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... plate fusion -> acromegaly ... rare causes of acromegaly ... hemianopsia IGF-1 Overproduction ... #Excess #Overproduction
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... Pathophysiology: • Acromegaly ... resistance pseudo-acromegaly ... thakre_anuj) #Acromegaly
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly ... GrowthHormone #GH
#ACROMEGALY #management #algorithm #treatment
#ACROMEGALY #management
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Resistance • Acromegaly
Hirsutism - Differential Diagnosis
Defined as excessive dark, coarse, male-pattern hair growth
Hirsutism causes in premenopausal women:
 •
Cushing's Syndrome, Acromegaly ... Cushing's Syndrome, Acromegaly
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Pituitary path • Acromegaly
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... Growth Hormone (GH ... ARUPConsult @ARUPLabs #Acromegaly
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... Clinical #Photo #Acromegaly ... #Acromegalic #Hand