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management oncology differential leukemia chronic cll mds myelodysplastic rheumatology acute aplastic bariatric bypass cardiology cd4 classification complications cvid endocarditis extravascular
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
CLL) - Summary Overview ... : • Most common ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... • Neutropenia, anemia ... microglobulin Treatment ... #Leukemia #diagnosis ... workup #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... Edema in 70% of cases ... Atypical Lymphocytes ... disease: symptomatic treatment ... #Syndrome #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... Drugs (Beta lactam antibiotics ... #hematology #anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Overview Who ... and petechiae Causes ... - β-lactam antibiotics ... Treatment: ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #causes #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Most common cytopenia ... isoniazid) • Antibiotics ... #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
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