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leukemia mds product reactions chronic classification cll cvid differential hodgkins hypogammaglobulinemia immunodeficiency immunology lymphocytic lymphoma myelodysplasia neutropenia syndromes transfusion transfusions
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... - Overview Who ... • Aplastic anemia ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... • Anemia • Aplastic ... isoniazid) • Antibiotics ... #Syndromes #diagnosis ... #hematology #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... Megaloblastic anemia-rare ... including white blood ... cell aplasia DOI ... #causes #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
(FNHTR): Most common ... progresses to pancytopenia ... due to marrow aplasia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... progresses to pancytopenia ... due to marrow aplasia ... #Transfusions #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... • Neutropenia, anemia ... Pure red cell aplasia ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma Overview ... nodosum • Immune hemolytic ... anemia • Pain ... classification #hematology ... #oncology #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
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