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management hematology tuberculosis latenttb als amyotrophic anemia aplastic apml bronchiectasis cauda caudaequina causes classification differentiation encephalopathy equina hodgkins immune inflammatory
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... tuberculosis (LTBI) Pathophysiology ... TB: • HIV • Recent ... • HIV: 2/3 pulmonary ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... tuberculosis (LTBI) Pathophysiology ... TB: • HIV • Recent ... • HIV: 2/3 pulmonary ... #Treatment #ActiveTB
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... - Overview of IRIS ... • Persistently active ... #Inflammatory #Syndrome ... #Differential #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... initiation • Differential ... #oncology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... #Tuberculosis #diagnosis ... #differential # ... TB #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Overview Cauda ... Diagnosis: • ... cord infarct • HIV ... T2 Treatment ... #neurology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Infection: TB ... Laboratory: • ANA ... • HIV, Immunoglobulins ... #differential #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
(PRES) Overview ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... #Diagnosis #Rheumatology
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